Metabolism Module 1 Topic 5 Pyruvate Pathways

11 flashcards · Other · by Haroon Chehabzada

1. What are three fates of pyruvate produced by glycolysis

   • Anaerobic Oxidation (lactic acid fermentation) • Anaerobic (alcoholic fermentation) • Aerobic Oxidation

2. Why does glucose undergo glycolysis

   To produce pyruvate

3. Under anaerobic conditions, why does pyruvate create ?

   ferments to lactic acid or ethanol

4. Under aerobic conditions, what does pyruvate get converted into ?

   acetyl-CoA

5. How does pyruvate conversion occurs ?

   Via pyruvate dehydrogenase complex

6. Pyruvate Dehydrogenase Complex is composed of what three enzymes ?

   dehydrogenase (E1), dihydrolipoyl transacetylase (E2), and dihydrolipoyl dehydrogenase (E3)

7. What coenzymes are involved in Pyruvate Dehydrogenase Complex ?

   Thiamine pyrophosphate (TPP), flavin adenine dinucleotide (FAD), nicotinamide adenine dinucleotide (NAD+), and lipoic acid

8. What is the active component of E2?

   It is composed of a polypeptide chain containing lipoyllysine and a molecule of lipoic acid

9. Coenzyme A Structure is composed of

   reactive thiol group and other functional groups in a structure of pantothenic acid, cysteamine, and adenosine diphosphate

10. What is the point of fermentation?

    Fermentation enables NAD+ to be recycled in the absence of oxygen, allowing ATP production to continue

11. Draw the structure of pyruvate