PCB 3023 - Molecular Cell Biology

22 flashcards · Biology · by brotherjack

1. What are the input/output molecules of the 6th step of the krebs cycle (with number of carbon atoms)?

   Input: Succinate (4C) (or SA) Output: Fumarate (4C)

2. What is the 7th and penultimate step of the krebs cycle?

   Hydrogenation of FA

3. What biochemical event occurs as part of the 7th and and penultimate step of the krebs cycle?

   H_2O is consumed

4. What are the input/output molecules of the 7th and penultimate step of the Krebs cycle (with the number of carbon atoms)?

   Input: Fumarate (4C) Output: Malate (4C) (or MA)

5. What is the 8th and final step of the Krebs cycle?

   Oxidation of malate (or MA)

6. What biochemical event occurs as part of the 8th and final step of the Krebs cycle?

   NAD+ is reduced to NADH

7. What are the input/output molecules in the 8th and final step of the Krebs cycle (with the number of carbon atoms)?

   Input: Malate (4C) (or MA) Output: Oxaloacetate (4C)

8. What is the third step of the krebs cycle?

   Oxidation of Isocitrate (6C)

9. What molecule is the output of the first step of the krebs cycle and how many carbons atoms does it have?

   Citric acid (6C) (AKA Citrate)

10. What is the first step of the krebs cycle and what drives the biochemical process?

    Step 1: Condensation / citrate synthesis Driven by hydrolysis that removes CoA

11. What is the input/output molecules of the second step of the krebs cycle (with number of carbon atoms)?

    Input: Citric Acid (6C) Output: Isocitrate (6C)

12. What is the second step of the krebs cycle?

    Isomerization of citric acid

13. What are the two events that happen as a part of the third step of the krebs cycle?

    1. CO2 is removed 2. NAD+ is reduced to NADH

14. What are the input/output molecules of the third step of the krebs cycle (with the number of carbon atoms)?

    Input: Isocitrate (6C) Output: Alpha-ketoglutarate (5C)

15. What is the 4th step of the krebs cycle?

    Oxidation of alpha-ketoglutarate (αKG is also acceptable)

16. What are the three biochemical events that occur in the 4th step of the krebs cycle?

    - CO2 removed - NAD+ reduced to NADH - CoA added

17. What are the input/output molecules of the 4th step of the krebs cycle (with carbon atom numbers)?

    Input: alpha-ketoglutarate (or αKG) (5C) Output: Succinyl CoA (or SCoA) (4C)

18. What is the 5th step of the krebs cycle?

    Hydrolysis of SCoA

19. What are the four biochemical events that occur as part of the 5th step of the Krebs cycle?

    - CoA removed - GTP synthesis - GTP is hydrolyzed - ATP synthesis

20. What are the input/output molecules of the 5th step of the krebs cycle (with number of carbon atoms)?

    Input: Succinyl CoA (4C) (or SCoA) Output: Succinate (4C) (or SA)

21. What is the 6th step of the krebs cycle?

    Oxidation of succinate

22. What biochemical event occurs at the 6th step of the krebs cycle?

    FAD is reduced to FADH_2