IB Biology: Ventilation
12 flashcards · Other · by Gabrielle Wong
Ventilation: the process of respiration, gas exchange, and cellular respiration
Important asepcts of alveoli structure:
Alveoli are sacs in lungs surronded by capillaries, the locaation of gas exchange Millions of alveoli in lung to increase SA for gas exchange Thin, single-layer walls for easy exchange of materials Blood capilarries with similar cells - minimal distance needed for gas to travel Type II Pneumocyes that produce a surfactant so oxygen can dissolve and diffuse and to decrease surface tension
Mechanism of breathing
Increased CO2 due to cellular respiration Threshold is reached Chemoreceptors detect Medullar oblongta sends nerve signals Nerve signals lead to contraction of diagphragm and external intercostal muscles Diagphragm moves down, pushing abdomen out, leading to a volume increase and pressure decrease Decreasing pressure creates a vaccum, leading to inspiration Stretch receptors sense the increase in volume, stopping the process Opposite muscle movement occurs Volume decreases, increasing pressure…
Antagonistic muscles: muslces that come in pairs (when one contracts, the other relaxes)
Example: Diaphragm and abdominal muscles are a pair
Intercostal muslces: muscles that move the thoriac cavity, made of external and internal muscles
External intercostal muscles: inhalation, expand volume of chest cavity Internal intercostal muscles: invovled in exhalation, decrease volume
Emphysema
Condition in which alveoli are destoryed throug hteh creaiton of irregularly shaped holes Caused by smoking tobacco/cannabis, manufacturing fumes etc. Leads to reduced SA for gas exahcne, damaging airways leading to alveoli No cure - mitigate risk by not soking, medication can provide relief, but eventually an oxygen tank is necessary
Lung cancer
Uncontrolled cell growth (tumor) in the lungs, prone to metastasis Caused by carcinogens, destorys lungs, may lead to internal bleeding, can be treated but has a high mortality rate
Chemosensors: found in aorta and cartoid arteries to detect increases of CO2 and subsequent decreases in pH, which then send signals to the medulla oblongta, which will increase the rate of breathing
The mechanism of breath doesn't change, just the frequency of the process
pH buffering: the mechanisms that lead to the maintenacne of pH within the range of 7.35-7.45
Temporary binding to hemoglobin Bound to proteins as solutes in plasma
Mountain sickenss: a result of air pressure decreasing, leading to less efficient diffusion of oxygen into alveoli, causes fatigue, vision problems, higher pulse
Some adaptions that occur as a result of living at a higher altitude: Larger lungs Increased capillaries Increased levels of hemoglobin and myoglobin
Oxygen dissociation curves: patterns that explain how attracted molecules are to oxygen depending on the partial pressure of oxygen
There is a curve for: Hemoglobin Myoglobin (muscle protein with a higher affinity for oxygen, only releases it in low-oxygen conditions to prevent the onset of lactic acid fermentation) Fetal hemoglobin (similar pattern as myoglobin allowing fetus to access oxygen from mother)
Bohr shift: hemoglobin has a lower affinity for oxygen at higher concentrations of CO2
Occurs because hemoglobin changes its shape when bound to CO2, decreasing its ability to retain O2