IB Biology: Neurones
13 flashcards · Other · by Gabrielle Wong
The nervous system
Processing system to respond to the outside world
Types of nerves/neurones: central nervous system: brain and spinal chord peripheral nervous system: other nerves cranial nevres: 12 pairs of nerves emerging from the brain spinal nerves: come from spinal chord, 31 pairs relay neurones: the connection of sensory and motor neurones sensory neurones: take information to CNS motor neurones: take information to muscles
Divisions are somewhat arbitrary since everything is connected anyways
Neurone structure: dendrite: nerve fibres branching out to increase surface area cell body axons: elongated nerve fibre Schwann cells: creates the Myelin sheath nodes of Ranvier: gaps in-between sheath synaptic terminals at the end
Nerve impulses
The transmission of a one-way electrical signal from dendrite to axon
Action potential:
Self-propagating wave of ions in and out of a neuron membrane (first starts with a receptor neurone which transmits physical stimulus into first potential once thershold potential is met)
Resting potential: state in which the neurone is ready to send an impulese, but isn't
The charge at this point is -65 mV, created due to the sodium-potassium pump. Potassiums and in the neurone, soidum is out.
Threshold potential:
point at whcih there is significant stimulus for a receptor neurone to transmit that stimulus into the first action potential ex. retina cells and light
The process of an action potential Depolarization: sodium channels open, sodium diffuses in, charge becomes +35 mV next part of axon opens up channels as a result reploraization: potassium repelled, potassium channels open, charge returns to -65 mV sodium-potassium pump must move potassium in and sodium out to return to resting channel
Refractory period: type between repolarization and resting potential Hyperpolarization: occurs briefly when K+ ions are moving out, corrected by the pump
Action Potential Diagram
Saltatory Conduction: term for action potentials that are propagated from one node of Ranvier to the next, increasing the speed of transmission and lowering the amount of ATP used since the Na-K pump works less
This occurs becuase the myelin sheath is an insulator, the cytoplasm is conductive, but the phospholipid bilayer Shwann cells prevent charge leakage
Neurotransmitter: small molecule (usually a single amino acid or derivative of a protein) that transport nerve impulses across synapses
Example: acetylcholine, a excitatory neurotransmitter found especially between neurones and muscle fibres, bonds and generates one action potential by increasing the permability of the post-synaptic receptor to positive ions Broken down by acetylcholinesterase, choline reabosrboed for resuse, acetyl group binding to another choline
Transmision of a nerve impulse across a synaptic junction:
Synapse: junction between neurones action potential travels to end of neurone ca+ ions diffuse in vesicles with nuerotransmietter fuse with membrane, release neurotransmitter neurotransmitter travels across synaptic cleft binds to receptor sodium channel opens, leading to one action potential enzyme degrades neurotransmitter ion channel closes neurotransmitter fragments diffuse
Insectides:
Neonicotinoid insectides: new insectide chemcially similar to nicotine, binds to post-synaptic receptors that normally accept acetylcholine When bound: Action potential can't be propagated receptor is permanently blocked neonitinoid can't be broken down Result: -insect is paralyzed, eventually dies