IM:腎內
32 flashcards · Other · by Wanying Koh
hyporeninemic hypoaldosteronism K, Na, acid levels
high K, high acid, low Na (aldosterone 留Na排K,acid) metabolic acidosis w hyperK
long term thiazide diuretics use metabolic acidosis or alkalosis Cl responsive or non-responsive
metabolic alkalosis Cl responsive (Urine Cl <20)
acetazolamide meta / respiratory acid/alkalosis? which ion imbalance?
cause HCO3- loss (reabsorption dec.) --> metabolic acidosis hypoK
nephrotic syndrome effective blood volume
PALE (proteinuria, hypoALB, hyperlipidemia, edema) 因為 loss of albumin --> dec osmotic pressure --> fluid shifts out of blood into extracellular and intracellular --> effective blood volume dec ECF increase ICF increase effective blood volume decrease
SIADH tx
first line: fluid restriction hypertonic saline (3% N/S) NOT 0.9%
tx of hypoaldosterone
0.9% N/S isotonic saline
補充 K during hypokalemia tx 不能用什麼
KCl + N/S dont use dextrose or glucose --> release of insulin, causing K to enter cells
renal tubular acidosis 什麼可以同時治療 acidemia & hypoK
potassium citrate
Bartter's syndrome & Gitelman syndrome 特性
metabolic alkalosis, low/normal BP, hypoK, hypoMg GDt BLf Bartter's: @loop of henle, like furosemide --> urine Ca inc., blood Ca dec (記得furosemide 排 Ca) Gitelman's: @distal tubule, like thiazide --> urine Ca dec, blood Ca inc
hyperkalemia 跟 meta acidosis/alkalosis 有關?
metabolic acidosis
hyperthyroidism causes hyperK or hypoK?
hypoK hyperthyroidism --> affects Na-K-ATPase channel (Na out, K in)
造成 constipation (low GI motility) K levels Ca levels thyroid hyper or hypo
K: hypo (weaker GI muscle contractions) Ca: hyper thyroid: hypo
hypoCa caused by Mg levels thiazide? furosemide? CKD? PTH levels
Mg levels - LOW thiazide - FALSE. causes hyperCa furosemide - TRUE. causes hypoCa 排 Na, K, Cl, Ca, Mg CKD - TRUE PTH levels - LOW
acute pancreatitis association w Ca levels
hyperCa --> acute pancreatitis --> hypoCa
hypoMg due to what syndromes (x3) thyroid hypo or hyper?
Gitelman, Bartter, refeeding syndrome hypothyroidism
delirium, Cr increased from 7.5 --> 9.6 in 1 week, kidney size small Dx Tx
uremic encephalopathy dialysis
RBC cast+, CXR pulmonary infiltrates, proteinuria trace, inc. BP Dx
pulmonary renal syndrome Goodpasture's syndrome RPGN SLE
FeNa formula
(UNa/PNa) / (UCr/PCr)
bacteria most associated with GN
Streptococcus
nephrotic syndrome associated w what cancer
hodgkin lymphoma
會有 low C3
Hep C (cryoglobulinemia) PSGN MPGN infective endocarditis lupus nephritis (NOT IgA nephropathy -- URTI 後 --> normal C3)
every year most common reason for new dialysis pts due to?
DM
earliest clinical symptom of DM nephropathy
GFR increase >120mL/min
most common nephritis in Taiwan adults
IgA nephropathy
13 year old boy with edema, hyperlipidemia, hypoalbuminemia, proteinuria Dx pathology
PALE nephrotic syndrome: minimal change dz similar to normal kidney
reuptake of HCO3- occurs in which part of nephron
proximal tubule
myogenic mechanism affects which arteriole causes what tubuloglomerular feedback affects which arteriole causes what
myogenic mechanism afferent arteriole to constrict/dilate based on BP tubuloglomerular feedback: if macular densa detects dec. in NaCl, causes: afferent - dilate (inhibit adenosine) efferent - constrict (inhibit renin, angiotensin II)
CKD anemia type ?chromic ?cytic anemia
normochromic normocytic anemia
uremic bleeding tx
DDAVP - tx and prophylaxis
stage 5 CKD, pericardial friction rub, hyperK, EKG ST-segment inc Dx? Tx?
uremic pericarditis dialysis
CAPD peritonitis most common 致病菌
Staphylococcus epidermidis GPC 60-70% GNB 15-20% 拔除透析導管
vomiting how does it cause hypoK
vomiting --> hyperbicarbonate --> K loss via renal --> hypoK vomiting --> volume depletion --> aldosterone inc --> 留Na排K