4。Neuro

8 flashcards · Other · by Wanying Koh

1. Myasthenia gravis tx

   thymectomy anticholinesterase drugs - pyridostigmine corticosteroids CANNOT use certain ABx during infection e.g. aminoglycosides, tetracycline, fluoroquinolone = action on NMJ worsen condition other contraindicated drugs procaine propranolol lithium chlorpromazine

2. levodopa compared to usual dopamine agonist difference

   AE will have more dyskinesia and motor fluctuations

3. myotonic dystrophy proximal or distal muscles affected genetic mutation involves facial m?

   distal affected AD genetic mutation of CTG repeats, 一代比一代嚴重 (genetic anticipation) yes, facial neck, hand, leg mescles affected

4. 好發族群 restless legs syndrome

   IDA pregnancy SSRI antidepressants RA ESRD peripheral neuropathy tx - dopamine agonist: pramipexole / ropinirole

5. lacunar infarction s/s

   pure sensory pure motor ataxic hemiparesis dysarthria sensorimotor hemiballism

6. narcolepsy s/s excessive daytime sleepiness cataplexy confusional arousal hypnagogic hallucination

   all except confusional arousal

7. Parkinson s/s tremor dysmetria reduced arm swing rigidity

   all except dysmetria dysmetria 為 cerebellum 問題

8. duchenne muscular dystrophy genetic mutation 有無 pseudohypertrophy

   x-linked recessive mutation in dystrophin gene yes